William Duddy
Stephanie Duguez
Apostolos Malatras
Matthew Thorley
Lu Zhu
Our objectives lie in translational approaches for neuromuscular disorders, including Duchenne muscular dystrophy and motor neuron disease (Amyotrophic Lateral Sclerosis).
Some tools and resources are linked above, and some of our work is highlighted here in the image slider.
Contact us at if you would like to collaborate on any muscle bioinformatics challenges.
Muscle Gene Sets example 1 (hTERT immortalization):
Thorley M et al. (2016) Skelet. Muscle 6(1):43
Muscle Gene Sets example 2 (ageing and SPRY1):
Bigot A et al. (2015) Cell Rep. 13(6):1172-82
Networks and subcellular localization:
Zhu L et al. (2015) Nucleic Acids Res. 43, W571–W575
Exon skipping drug design:
Echigoya Y et al. (2015) PLoS One 10(3)
Myofibre growth in DMD murine model:
Duddy W et al. (2015) Skelet. Muscle 5:16
Muscle systems analyses:
Duguez S et al. (2013), Cell. Mol. Life Sci. 70(12):2159-74